Dr.
Martin D'Souza's Home Page
Professor, Department of Pharmaceutical Sciences
Director of Graduate Programs, Director, Mercer Clinical Laboratory.
Co-Director Center for Drug Delivery Research
College of Pharmacy & Health Sciences, Mercer University-Atlanta, 3001 Mercer University Dr., Atlanta, GA 30341 Tel: (678) 547-6353 Fax: (678) 547-6423 Email: dsouza_mj@mercer.edu
Drug delivery
technology has infused new interest in seemingly ineffective drugs by targeting
them specifically to desired sites of action. In this manner, unwanted systemic
side effects and toxicity are obviated and dose requirements can be
substantially reduced.
Modern
immunology has acknowledged the importance of the monocyte /macrophage as the
prime antigen presenting cell in immune reactions. As an extension of this
function, macrophages may be utilized to present immuno-suppressant drugs to
relevant components of the immune system, such as lymphocytes in an effort to
down regulate aberrant or undesired expression. The deleterious effects of
autoimmune diseases that manifest themselves due to improper recognition of
“self” from “non-self” may be effectively abolished using this mode of delivery
– tumor therapy, organ transplantation, septic shock, AIDS and rheumatoid
arthritis are examples of such diseases.
We also have several specialty "Centers for Excellence" in the areas of Drug Delivery, Drug Analysis, and Pharmacokinetics. I welcome you to preview these different areas as listed below.
Links
Mercer Clinical Laboratory Center for Drug Delivery Research
Research Interests Graduate Students Patent Issued Manuscripts published
Publications Abstracts Invited Presentations
Scientific Presentations Research Grants & Contracts
