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Published Journal Articles
1. D'Mello, A., D’Souza, M.J., and Bates, T.R. Pharmacokinetics of the ketoconazole-antipyrine interaction in man. (Letter), Lancet vol. ii., 209-10, 1985
2. D’Souza, M.J., Venkataramanan, R., D'Mello, A., and Niphadkar, P. An alternative pro drug approach to reduce presystemic metabolism of drugs. International Journal of Pharmaceutics., 31, 165-167, 1986
3. D’Souza, M.J., Post-marketing drug surveillance. IDMA Bulletin , XVII (5), 1-4, 1986.
4. D’Souza, M.J., Zemaitis, M.A., Burckart G.J. and Venkataramanan R. Simple high-performance liquid chromatographic method for the simultaneous determination of aminopyrine and its metabolites. Journal of Chromatography, 421, 198-205, 1987
5. D’Souza, M.J., Pollock, S.H., and Solomon, H.M. Cyclosporine - Phenytoin Interaction. Drug Metabolism and Disposition, 16, 256-258, 1988
6. D’Souza, M.J., Controlled release of cyclosporine from microspheres. Drug Development and Industrial Pharmacy, 14 (10), 1351-1357, 1988
7. D’Souza, M.J., Pollock, S.H., and Solomon, H.M. Cyclosporine - Cimetidine Interaction. Drug Metabolism and Disposition, 16, 57-59, 1988
8. D’Souza, M.J., Fowler L., Solomon H., and Pollock, S.H., Pharmacokinetics of cyclosporine in streptozotocin induced diabetic rats. Drug Metabolism and Disposition,16, 778-780, 1988.
9. D’Souza, M.J., Gourdikian K., and Mujukian A., Comparison of cyclosporine A and G pharmacokinetics. Drug Metabolism and Disposition, 16, 895-897, 1988.
10. D’Souza, M.J., Solomon H.M., and Lowance, D., Effect of chronic treatment with cyclosporine and prednisolone on acetaminophen metabolism in renal transplant patients. Transplantation, 48,697-700,1989
11. Pollock S.H., Matthews, H.W., and D’Souza, M.J., Pharmacokinetic analysis of cyclosporine in adjuvant arthritic rats. Drug Metabolism and Disposition, 17, 6, 595-599, 1989
12. Stokar, L., Burckart G.J., D’Souza, M.J., Cohen B., and Venkataramanan, R., Topical cyclosporine administration in rabbits. Research Communications in Chemical Pathology and Pharmacology, 68,(1),117-120, 1990.
13. Grimsley S, Jann, M., Carter G, D'Mello A, and D’Souza, M.J., Increased carbamazepine plasma concentrations after fluoxetine coadministration. Clinical Pharmacology & Therapeutics, 50, 10-15, 1991
14. Pollock, S.H., Reichbaum M.I, Collier, B.H, D’Souza, M.J., Inhibitory effect of Cyclosporine A on the activity of Oral Hypoglycemic Agents in rats. Journal of Pharmacology & Experimental Therapeutics, 258, 8-12, 1991
15. Dewell WM, Khandaghabadi M, D’Souza M.J and Solomon H. M., High performance liquid chromatographic determination of fentanyl and sufentanyl returned from the operating room. (Note). American Journal of Hospital Pharmacy. 50, 2374- 2375, 1993
16. Job M, Arn S, Strom G, Jacobs N, and D’Souza, M.J., Effect of ciprofloxacin on the pharmacokinetics of multiple dose phenytion serum concentrations. Therapeutic Drug Monitoring, 16,427-431, 1994
17. Gerber D.A., Oettinger, C., D’Souza, M.J., Milton G.V., Larsen C.P. and Pearson T.C., Prolongation of murine cardiac allograft sruvival by microencapsulated TNF-alpha and IL-1B. Journal of Drug Targeting, 3, 311-315,1995
18. D’Souza M.J. and DeSouza, P.J., Site specific microencapsulated drug targeting strategies to the liver and the gastrointestinal tract. Advanced Drug Delivery Reviews, 17,247-254,1995.
19. Oettinger, C., DSouza, M.J. and Milton, G., In Vitro comparison of cytokine release from anti-thymocyte serum and OKT3, Transplantation, 62,11, 1996
20. Huang X, Tipping P, Apostolopoulos J, Oettinger, C., D’Souza, M.J., Milton G and Holdsworth S., Mechanism of T cell-induced glomerular injury in anti-glomerular basement membrane (GMB) glomerulonephritis in rats. Clinical and Experimental Immunology, 109,134-142,1997.
21. Anderson R.J., D’Souza, M.J., Grapes Z.T., Kavula M and Miller S.W., Promotion and Tenure – Do criteria and process differ? (Letter). American Journal of Pharmaceutical Education, vol. 62, Fall 1998
22. D’Souza M and DeSouza, P., Preparation and testing of cyclosporine microsphere and solution formulations in the treatment of polyarthritis in rats. Drug Development and Industrial Pharmacy., 24 (9), 841-852,1998
23. D’Souza M and Pourfarzib, R., Improved efficacy of a microencapsulated macrophage colony stimulating factor and methotrexate in melanoma. Drug Development and Industrial Pharmacy. 25 (5), 585-592, 1999
24. Oettinger, C., D’Souza, M.J., and Milton, G., Evaluation of microspheres containing cytokine neutralizing antibodies in endotoxemia. Drug Development and Industrial Pharmacy, 25 (6), 727-734, 1999.
25. D’Souza, M.J., Oettinger, C., Shah, A., Tipping P, Xiao Huang, and Milton, G., Macrophage depletion by albumin microencapsulated clodronate: attenuation of cytokine release in macrophage dependent glomerulonephritis. Drug Development and Industrial Pharmacy. 25 (5), 591-596, 1999
26. Shah, A., and D’Souza, M.J., Sustained release of interleukin-12 microspheres in the treatment of cancer. Drug Development and Industrial Pharmacy, 25 (9), 21-30, 1999.
27. Green, M., Bergqvist, Y., Mount, D., Corbett, S., and D’Souza, M.J., Improved validated assay for the determination of mefloquine and its carboxy metabolite in plasma serum and whole blood using solid-phase extraction and high performance liquid chromatography. Journal of Chromatography B, 727, 159-165, 1999
28. Oettinger, C., D’Souza, M., and Milton, G., Targeting macrophages with microspheres containing cytokine-neutralizing antibodies prevents lethality in gram-negative peritonitis. Journal of Interferon and Cytokine Research. 19, 33-40, 1999
29. D’Souza, M.J., Oettinger, C., Milton, G., and Tracey, K., Prevention of lethality and suppression of pro-inflammatory cytokines in experimental septic shock by microencapsulated CNI-1493. Journal of Interferon and Cytokine Research. 19, 1125-1133, 1999
30. Tong, W., Wang, L. and D’Souza M.J. Evaluation of PLGA microspheres as delivery system for anti-tumor agent- camptothecin. Drug Development and Industrial Pharmacy, 29, 7, 745-756, 2003
31. Oettinger C, and D’Souza MJ. Microencapsulation of tumor necrosis factor oligomers: A new
approach to proinflammatory cytokine inhibition. J. Interferon and Cytokine Research, 23, 533-543, 2003.
32. Green M, D’Souza MJ, Holbrook JM and Wirtz RA. In-vivo and in-vitro evaluation of albumin-encapsulated primaquine diphosphate prepared by nebulization into heated oil. Journal of Microencapsulation, 21(4): 433- 44, 2004
33. Bumgarner GW, Zampell JC, Nagarajan S, Poloso NJ, Dorn AS, D'Souza MJ, Selvaraj P. Modified cell ELISA to determine the solubilization of cell surface proteins: Applications in GPI-anchored protein purification. J Biochem Biophys Methods. 64(2): 99-109, 2005
34. D’Souza MJ, Jin Z and Oettinger C W. Treatment of experimental septic shock with microencapsulated antisense oligomers to NF-kappaB. J Interferon Cytokine Res. 25(6): 311-20, 2005
35. Nettey H., Haswani D., Oettinger C.W., D’Souza M.J., Formulation and Testing of Vancomycin Loaded Albumin Microspheres Prepared by Spray-drying. J. of Microencapsulation. 23:632-642, 2006.
36. Haswani D., Nettey H., Oettinger C., D’Souza M. Formulation, characterization and pharmacokinetic evaluation of gentamicin sulphate loaded albumin microspheres. J. of Microencapsulation 23:875-886, 2006.
37. Lai Y.H. and D’Souza M.J. Formulation and evaluation of an oral melanoma vaccine. J. Microencapsulation 24, (3), 235-252, 2007
38 Haswani D., Nettey H., D’Souza M., Oettinger C. In-vitro evaluation and targeting of E.Coli internalized by endothelial cells using albumin microspheres loaded with gentamicin. Drug Development and Industrial Pharmacy 33:181-90, 2007
39 Oettinger C., D’Souza M., Akhavein N., Peer G., Taylor F., Kinasewitz G. Pro-Inflammatory cytokine inhibition in the primate using microencapsulated antisense oligomers to NF-kB. J. Microencapsulation, 24(4): 337-348, 2007.
40. Zhaowei J., D’Souza, M.J., and Oettinger, C.W., Reversal of LPS induced endothelial cell TNF synthesis and increased permeability with microencapsulated antisense oligomers to NF-kappa B. J. Microencapsulation. 24 (6): 596- 607, 2007.
41. Nettey H., Haswani D., D’Souza M., Oettinger C. In-vitro anti-microbial effect of encapsulated
vancomycin on internalized Staph. Aureus within endothelial cells. Drug Development and Industrial Pharmacy 33 (2): 133-9, 2007.
42. Oettinger C., D’Souza M., Akhavein N., Peer G., Taylor F., Kinasewitz G. Pro-Inflammatory cytokine inhibition in the primate using microencapsulated antisense oligomers to NF-kB. J. Microencapsulation, 24(4): 337-348, 2007.
43. Lai Y.H. and D’Souza M.J. Formulation and evaluation of an oral melanoma vaccine. J. Microencapsulation, 24, (3), 235-252, 2007
44. Haswani D., Nettey H., D’Souza M., Oettinger C. In-vitro evaluation and targeting of E.Coli internalized by endothelial cells using albumin microspheres loaded with gentamicin. Drug Development and Industrial Pharmacy 33:181-90, 2007
45. Nettey H., Haswani D., D’Souza M., Oettinger C. In-vitro anti-microbial effect of encapsulated vancomycin on internalized Staph. Aureus within endothelial cells. Drug Development and Industrial Pharmacy 33 (2): 133-9, 2007.
46. Bejugam N.K., Sou M., Uddin, A.N., Gayakwad S.G., and D’Souza M.J. Effect of Chitosans and other excipients on the Permeation of Ketotifen, FITC-Dextran and Rhodamine 123 through Caco-2 Cells. Journal of Bioactive and Compatible Polymers. 23, No. 2, 187-202 (2008)
47. Lai Y.H and D’Souza M.J. Microparticle transport in the human M cell model. Journal of Drug Targeting, 16(1), 36-42, 2008
48. Lanke SS, Gayakwad SG, Strom and D’Souza MJ. Oral delivery of low molecular weight heparin microspheres prepared using biodegradable polymer matrix system. Journal of Microencapsulation, 9:1-8.(2008)
49. Siwale RC, Oettinger CW, Balakrishna P, Addo R, Uddin N, Siddig A and D’Souza MJ. Formulation and characterization of catalase in albumin microspheres. Journal of Microencapsulation, 23:1-9. (2008)
50. Akhavein N, Oettinger C, Gayakwad S, Addo R, Bejugam N, Bauer J, Do D, Pollock S and D’Souza MJ Treatment of adjuvant arthritis using microencapsulated antisense NF-kappaB oligonucleotides. Journal of Microencapsulation, 18:1-12. (2008)
51. Bejugam NK, Uddin AN, Gayakwad SG, D'Souza M.J Formulation and evaluation of albumin microspheres and its enteric coating using a spray-dryer.. Journal of Microencapsulation; 25(8): 577-83, (2008)
52. Bejugam N.K., Sou M., Uddin, A.N., Gayakwad S.G., and D’Souza M.J. Effect of Chitosans and other excipients on the Permeation of Ketotifen, FITC-Dextran and Rhodamine 123 through Caco-2 Cells. Journal of Bioactive and Compatible Polymers. 23, No. 2, 187-202 (2008)
53. Yeboah K., and D’Souza M Evaluation of albumin microspheres as oral delivery systems for Mycobacterium tuberculosis vaccines. Journal of Microencapsulation, 26(2):166-79. (2009)
54. Gayakwad SG, Bejugam NK, Akhavein N, Uddin NA, Oettinger CE, D'Souza MJ Formulation and in vitro characterization of spray-dried antisense oligonucleotide to NF-kappaB encapsulated albumin microspheres. Journal of Microencapsulation. 26(8):692-700, 2009.
55. Angra PK, Siddig A, Nettey H, Desai N, Oettinger C, D'Souza MJ Pharmacokinetic and biodistribution studies of Amphotericin B microspheres. Journal ofMicroencapsulation. 26(7):627-34, 2009
56. Siwale RC, Yeboah GK, Addo R, Oettinger CW, D'Souza M.J., The effect of intracellular antioxidant delivery (catalase) on hydrogen peroxide and proinflammatory cytokine synthesis: a new therapeutic horizon. Journal of Drug Targeting. 17(9):710-8, 2009
57. Angra PK, Oettinger C, Balakrishna Pai S, D'Souza MJ.Amphotericin B microspheres: A therapeutic approach to minimize toxicity while maintaining antifungal efficacy. Journal of Microencapsulation. 26(7):580-7, 2009
58. Siwale RC, Oettinger CW, Addo R, Siddig A, D'Souza MJ. The effect of intracellular delivery of catalase and antisense oligonucleotides to NF-kappaB using albumin microcapsules in the endotoxic shock model. Journal Drug Targeting. 17(9):701-9, 2009
59. Uddin AN, Bejugam NK, Gayakwad SG, Akther P, D'Souza MJ. Oral delivery of gastro-resistant microencapsulated typhoid vaccine. Journal of Drug Targeting. 17(7):553-60, 2009
60. Uddin M., Do D, Pai S., Gayakwad, S., Oettinger C and D’Souza, M.J., A Methodology for Quantitation and Characterization of Oligonucleotides in Albumin Microspheres. Analyst, 134(7):1483-9. 2009
61. Bumgarner GW, Shashidharamurthy R, Nagarajan S, D’Souza MJ, and Selvaraj P. Surface engineering of microparticles using a novel protein transfer technique: Potential applications in targeted drug delivery and vaccine adjuvant development. Journal of Controlled. Release 20; 137(2):90-7. 2009.
62. Lai YH, D'Souza MJ. Labeling of Fluorescent Probes to Albumin Microspheres and B16 Melanoma Extra-Cellular Antigen. Current Drug Delivery. 2010; 7 (3); 188-193.
63. Oettinger CW, D'Souza MJ. Synergism in survival to endotoxic shock in rats given microencapsulated CNI-1493 and antisense oligomers to NF-kappaB. Journal of Microencapsulation. 2010; 27(4):372-6
64. Okoroukwu ON, Green GR, D'Souza MJ. Development of albumin microspheres containing Sp H1-DNA complexes: a novel gene delivery system. Journal of Microencapsulation, 2010; 27(2):142-9.
65. Akande J, Yeboah KG, Addo RT, Siddig A, Oettinger CW, D'Souza MJ.; Targeted delivery of antigens to the gut-associated lymphoid tissues: 2. Ex vivo evaluation of lectin-labelled albumin microspheres for targeted delivery of antigens to the M-cells of the Peyer's patches. Journal of Microencapsulation. 2010;27(4):325-36
66. Addo RT, Siddig A, Siwale R, Patel NJ, Akande J, Uddin AN, D'Souza MJ. Formulation, characterization and testing of tetracaine hydrochloride-loaded albumin-chitosan microparticles for ocular drug delivery.; Journal of Microencapsulation. 2010;27(2):95-104.
67. Bozeman EN, Shashidharamurthy R, Paulos SA, Palaniappan R, D'Souza M, Selvaraj P., Cancer vaccine development: designing tumor cells for greater immunogenicity. Frontiers in Biosciences. 2010 ;15:309-20.
68. Jones AK, Bejugam NK, Nettey H, Addo R, D'Souza MJ. Spray-dried doxorubicin-albumin microparticulate systems for treatment of multidrug resistant melanomas. Journal of Drug Targeting. 2011, 19(6):427-33
69. Angra, P., Rizvi, S., Oettinger, C., D’Souza, M. Novel Approach for Preparing Nontoxic Stealth Microspheres for Drug Delivery, European Journal of Chemistry,2011, 2(2), 125-129
70. Bhowmik, T., D’Souza, B., Selvaraj, P., Shashidharamurthy, R., Oettinger, C., D’Souza, M., A Novel Microparticulate Vaccine for Melanoma Cancer using Transdermal Delivery. Journal of Microencapsulation, 2011, 28(4):294-300,
71. Uddin, M., D'Souza, M., Siddig, A., Oettinger, C., Potentiation of pre-inflammatory cytokine suppression and survival by microencapsulated dexamethasone in the treatment of experimental sepsis. Journal of Drug Targeting. 2011 Nov;19(9):752-60, Sep 14. [Epub ahead of print]
72. D'Souza B, Bhowmik T, Shashidharamurthy R, Oettinger C, Selvaraj P, D'Souza M. Oral microparticulate vaccine for melanoma using M-cell targeting. J Drug Target. 2012, Feb; 20(2):166-73, Oct 10. [Epub ahead of print]
73. Chablani L, Tawde SA, D'Souza MJ. Spray-dried microparticles: a potential vehicle for oral delivery of vaccines. J Microencapsul. 2012 Jan 27. [Epub ahead of print]
76. Oettinger CW, D'Souza MJ. Microencapsulated drug delivery: a new approach to pro- inflammatory cytokine inhibition. J Microencapsul. 2012 Feb 21. [Epub ahead of print]
77. D'Souza B, Bhowmik T, Shashidharamurthy R, Oettinger C, Selvaraj P, D'Souza M. Oral microparticulate vaccine for melanoma using M-cell targeting. J Drug Target, 2012, 20, 166-73.
78. Akalkotkar A, Tawde SA, Chablani L, D'Souza MJ. Oral delivery of particulate prostate cancer vaccine: In vitro and in vivo evaluation. J. Drug Target, 2012, 20, 338-46
79. Bhowmik T, D'Souza B, Uddin MN, D'Souza MJ. Oral delivery of microparticles containing plasmid DNA encoding hepatitis-B surface antigen. J Drug Target, 20, 364-71.
80. Uddin MN, Patel NJ, Bhowmik T, D'Souza B, Akalkotkar A, Etzlar F, Oettinger CW, D'Souza MJ. (2013). Enhanced bioavailability of orally administered antisense oligonucleotide to nuclear factor kappa B mRNA after microencapsulation with albumin.J Drug Target. 21(5):450-7.
81. Pandey A, Kurup A, Shrivastava A, Radhi S, Nguyen DD, Arentz C, D'Chuna N, Hardwick F, D'Souza MJ, Jenkins M, Grizzi F, Kast WM,Cobos E, Rahman R, Chiriva-Internati M, Chiaramonte R, Platonova N. (2012), Cancer testes antigens in breast cancer: biological role, regulation, and therapeutic applicability. Int Rev Immunol. 31(5):302-20.
82. Ubale RV, D'Souza MJ, Infield DT, McCarty NA, Zughaier SM., (2013) Formulation of meningococcal capsular polysaccharide vaccine-loaded microparticles with robust innate immune recognition.J Microencapsul. 30(1):28-41
83. Chablani L.,Tawde SA. Akalkotkar A., D'Souza C., Selvaraj P., D'Souza MJ., (2012), Formualtion and evaluation of a particulate oral breast cancer vaccine. J. Pharm. Sci, 101 (10):3661-71
84. Shastri PN, Ubale, R, Kang SM, D'Souza MJ. (2012) Immunogenicity and protection of oral influenza vaccines formulated into microparticles. J. Pharm.Sci, 101(10):3623-35.
85. Enriquez GG, Rizvi SA, D'Souza MJ, Do DP. (2013) Formulation and evaluation of drug-loaded targeted magnetic microspheres for cancer therapy. Int J Nanomedicine. 8:1393-402.
86. Bejugam NK, Gayakwad SG, Uddin AN, D'Souza MJ. (2013). Microencapsulation of protein into biodegradable matrix: a smart solution cross-linking technique. J Microencapsul. 30(3):274-82
87. Tawde SA, Akalkotker A, D’Souza C, Chiriva-Internati M, Selvaraj P, D’Souza MJ (2012) Formulation of Oral Microparticulate Ovarian Cancer Vaccines, Vaccine, 17, 30 (38):5675-81
88. Kolluru LP, Rizvi SA, D'Souza M, D'Souza MJ. (2013). Formulation development of albumin based theragnostic nanoparticles as a potential delivery system for tumor targeting. J Drug Target. (1):77-86.
89. Shastri, P., Ubale R., D’Souza M.J. (2013). Implementation of mixture design for formulation of albumin containing enteric-coated spray-dried microparticles, Drug development and Industrial Pharmacy, (2):164-75.
90. D'Souza B, Bhowmik T, Uddin MN, Oettinger C, D'Souza M. Development of β-cyclodextrin-based sustained release microparticles for oral insulin delivery. Drug Dev Ind. Pharm. 2014 Aug 26:1-6.
91. Ubale RV, Gala RP, Zughaier SM, D'Souza MJ. Induction of death receptor CD95 and co-stimulatory molecules CD80 and CD86 by meningococcal capsular polysaccharide-loaded vaccine nanoparticles. AAPS J. 2014 Sep;16(5):986-93. Epub 2014 Jul 1.
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