Moniri Laboratory

Advancing GPCR pharmacology and translational science in metabolic, inflammatory, cardiovascular, neurodegenerative, and oncogenic diseases.

Principal Investigator

Dr. Nader H. Moniri
Professor of Pharmaceutical Sciences, College of Pharmacy
Professor of Biomecial Sciences, School of Medicine
Associate Dean for Research, College of Pharmacy

Dr. Moniri’s research program sits at the intersection of molecular pharmacology and drug discovery, with a primary focus on the signal transduction of G protein-coupled receptors (GPCRs). Our work spans from fundamental receptor characterization to the development of selective therapeutic agents for complex human diseases.

B.S. — Georgia State University Biological Sciences
Ph.D. — UNC-Chapel Hill, School of Pharmacy Medicinal Chemistry & Chemical Biology
Postdoctoral Training — Duke University Medical Center GPCR Biochemistry, Signaling and Regulation
Expertise GPCR pharmacology • Drug discovery • Cellular Physiology • Signal transduction

Research Focus Areas

Free-Fatty Acid Receptors

Metabolism, neurodegeneration, cardiovascular disease, inflammation, cancers.

Oxidative regulation of β2-adrenergic receptors

Role of ROS in β2-receptor function in airway and cardiovascular systems

GPCR Drug Discovery - Achmore Therapeutics

Novel M2-selective anti-muscarinic agents for bradycardia, neurodegeneration, addiction.

Cardiovascular disease

Signal transduction in hypertension.

Current Lab Members

Full Team & Lab Alumni
Monika Binwal

Monika Binwal, Ph.D., Post-Doctoral Fellow

Zahra Dehgan

Zahra Dehghan, Research Assistant I

Razan Teyani

Rezan Teyani, Ph.D. Student

Alex Rogier

Alex Rogier, Ph.D. Student

Farnoosh Moghaddam

Farnoosh Modhaddam, Ph.D. Student

Mohsina Mukti

Mohsina Mukti, Ph.D. Student

Ten Most Recent Publications

Full Publication List
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