PHA 321 - Biosciences II
Quiz 5 - March 12, 2004		

1.	The chains of an antibody molecule are bonded to one another by	
	A)  disulfide bonds.    B)  hydrogen bonds.    C)  ionic bonds.    D)  oxygen bonds.	

2.	Each class of antibody is specifically defined by its	
A)	amino acid sequence of the constant region of the heavy chain.	
B)	amino acid sequence of the variable region of the light chain.	
C)	ability to cross the placenta.	
D)	disulfide bonds.	

3.	Which is the first antibody class made during the primary response to an antigen?	
	A)  IgA    B)  IgM    C)  IgG    D)  IgE	

4.	Which of the following is the most abundant immunological class produced?	
	A)  IgA    B)  IgD    C)  IgG    D)  IgE
(the correct answer to this question is IgA, which is very abundant in the tissues)	

5.	The stimulation of B cells to divide and mature is provided by	
	A)  T helper cells.    B)  macrophages.    C)  T cytotoxic cells.    D)  plasma cells.	

6.	The peptides presented by MHC class II peptide molecules are	
A)	from plasma cells.	C)	endogenous antigens.	
B)	exogenous antigens.	D)	from T helper cells.	

7.	T-independent antigens	
A)	include polysaccharides.	D)	are usually proteins.	
B)	require the involvement of T cells.	E)	a and d	
C)	interact with MHCI molecules.			

8.	Memory cells may take the form of	
	A)  B cells    B)  T cytotoxic cells    C)  T helper cells    D)  all of the above	

9.	How long after initiation of a primary response do significant amounts of antibody appear in
 the blood?	
	A)  one day    B)  10-14 days    C)  4 weeks    D)  6 months	

10.	Ag-Ab binding may result in	
A)	neutralization	D)	opsonization	
B)	immobilization	E)	all of the above	
C)	agglutination