PHA 321 - Biosciences II
Quiz 3 - March 8, 2004	

1.	Interferons, complement, lysozyme, and lactoferrin are all examples of	
A)	specific antimicrobial factors.	C)	nonspecific antimicrobial factors.	
B)	immune enzymes.	D)	cytokines.	

2.	The complement pathway that requires antibodies to be activated is the	
A)	alternate pathway.	C)	antibody pathway.	
B)	classical pathway.	D)	inflammatory pathway.	

3.	The complement pathway that is activated by binding of C3b to cell surfaces is the	
A)	classical pathway.	C)	C3b pathway.	
B)	alternate pathway.	D)	mucociliary pathway.	

4.	C3a and C5a are involved in	
A)	inflammation.	D)	enhancement of phagocytosis.	
B)	interferon production.	E)	a and d	
C)	properidin activation.			

5.	Which of the following are most susceptible to complement lysis?	
	A)  Gram-positive bacteria    B)  Gram-negative bacteria    C)  bacteriophages    D)  prions	

6.	Interferons function to make cells	
A)	resistant to viral infection.	C)	non-motile when infected with virus.	
B)	lyse when exposed to virus.	D)	resistant to viral replication.	

7.	Which activity of the virally-invaded cell triggers production of interferon?	
A)	production of ds RNA	
B)	movement of nuclear proteins to the cytoplasm	
C)	production of glycolipids	
D)	production of ssRNA	

8.	Fever	
A)	enhances bacterial growth.	D)	triggers complement.	
B)	inhibits bacterial growth.	E)	b and c	
C)	slows down the body's reactions.			

9.	Toll-like receptors	
A)	are cytokines.	
B)	each recognize a specific "danger" molecule.	
C)	transmit a message by entering the cell's nucleus.	
D)	are part of adaptive immunity.	
E)	b and c	

         10.  All are outcomes of complement activation except
          A)  opsinization
          B)  cell lysis
          C)  secretion of interferon
          D)  inflammation
          E)  all of the above