Test potential drugs
The laboratory experience starts by testing previously made compounds against biofilm formation. This requires learning aseptic technique, proper handling of bacterial cells, use of microplate washers and readers, and data analysis.
Design your own
Using the data you collect along with past BOMM data, your group will devise a hypothesis and design new compounds to test against biofilms. Each group will design six new compounds using a combinatorial approach.
Synthesize and test your design
Using solid-phase synthesis techniques, your group will then construct the compounds, purify them, and test them in the biofilm assay-completing an entire iteration of the drug discovery process.
